Figure 1
Figure 1. Efferocytosis by X-CGD MØs is impaired ex vivo and in vivo. (A) BMDMØs were cultured for 6 days; RPMØs and thioelicited MØs were plated for 24 hours and efferocytosis assays performed as described in “Efferocytosis assay.” Data represent means plus or minus SEM; N = 5 experiments. (B) In vivo efferocytosis assays in the peritoneum and lung were performed as in “Efferocytosis assay.” Data represent means plus or minus SEM; N = 5 experiments. #P ≤ .05; *P ≤ .005 compared with respective WT.

Efferocytosis by X-CGD MØs is impaired ex vivo and in vivo. (A) BMDMØs were cultured for 6 days; RPMØs and thioelicited MØs were plated for 24 hours and efferocytosis assays performed as described in “Efferocytosis assay.” Data represent means plus or minus SEM; N = 5 experiments. (B) In vivo efferocytosis assays in the peritoneum and lung were performed as in “Efferocytosis assay.” Data represent means plus or minus SEM; N = 5 experiments. #P ≤ .05; *P ≤ .005 compared with respective WT.

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