Table 2

Changes in the expression of immune response genes associated with anti-CD2/CD28 activation of the CD3−CD4+ T cells from P1-P3

Changes in the expression of immune response genes associated with anti-CD2/CD28 activation of the CD3−CD4+ T cells from P1-P3

aOne probe (greatest fold change) is shown for each gene, except where differences were detected in individual probes to the same gene.

bFold change comparing the mean expression of duplicate arrays from P1, P2, and P3 nonstimulated with the mean expression from 4 controls; data are from supplemental Table 2.

cFold changes detected in the mean expression from triplicate arrays of P1 nonstimulated CD3−CD4+ T cells from yr +6 compared with yr 0; data are from supplemental Table 3.

dFold change comparing the mean expression of duplicate arrays from stimulated (S) vs nonstimulated (NS) CD3−CD4+ T cells from P1 to P3; data are from supplemental Table 2.

eGenes whose expression is similarly altered both after activation and in L-HES patient cells (either chronic disease or T lymphoma) are highlighted in gray.

fNC indicates no change.

gIn P1, CCL5 levels are decreased yr 0 vs C and yr +4 vs yr 0 but then increase in yr +6 vs yr 4 (supplemental Table 3).

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