Figure 4
Figure 4. KL-driven generation of wasp+/− BMMCs reveals a selective advantage for WASP-expressing cells. In 2 separate experiments that delivered corresponding results (1 shown), 3 cultures from wasp+/− BM were established at day 0 and maintained in the presence of KL as growth factor (40 ng/mL) for 90 days. Intracellular WASP expression was evaluated in the Kit-positive populations of the wasp+/− cultures (blue) and compared with that of the control wt (green) or wasp−/− (red) cultures by flow cytometry at the culture days indicated.

KL-driven generation of wasp+/− BMMCs reveals a selective advantage for WASP-expressing cells. In 2 separate experiments that delivered corresponding results (1 shown), 3 cultures from wasp+/− BM were established at day 0 and maintained in the presence of KL as growth factor (40 ng/mL) for 90 days. Intracellular WASP expression was evaluated in the Kit-positive populations of the wasp+/− cultures (blue) and compared with that of the control wt (green) or wasp−/− (red) cultures by flow cytometry at the culture days indicated.

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