Figure 3
ABT-737 decreases the clonogenic potential of Eμ-myc lymphomas overexpressing Bcl-2 and Bcl-XL. 4242 Eμ-myc/MSCV, Eμ-myc/Bcl-2, Eμ-myc/Bcl-XL, Eμ-myc/Bcl-w, Eμ-myc/Mcl-1, and Eμ-myc/A1 lymphomas were treated for 24 hours with 1.0 μM ABT-737 or an equivalent volume of DMSO (the ABT-737 diluent). Cells were plated in soft agar and clonogenic growth was assessed 6 days later. Results shown are the mean and SE from at least 3 separate experiments.
