Figure 6
Figure 6. Expression of chemokine receptors and homing molecules between CIK cells and splenocytes. Lethally irradiated host mice (Balb/c, H-2d) were injected with C57BL/6 (H-2b, Thy1.2) wild-type 5 × 106 BM cells with either 10 × 106 CIK cells or splenocytes generated from congenic C57BL/6 (H-2b, Thy1.1). Expression of chemokine receptors, homing molecules, and IFN-γ expressed on donor-derived cells were analyzed at indicated days and tissues after BMT by FACS. (A) α4β7 and CCR9. (B) E-selectin ligand and P-selectin ligand. (C) CCR5 and CXCR3. (D) IFN-γ. ND indicates not done. Samples were not obtained because all GVHD control mice died by day 9. LN indicates lymph node. Error bars represent SD. *P < .05; **P < .01.

Expression of chemokine receptors and homing molecules between CIK cells and splenocytes. Lethally irradiated host mice (Balb/c, H-2d) were injected with C57BL/6 (H-2b, Thy1.2) wild-type 5 × 106 BM cells with either 10 × 106 CIK cells or splenocytes generated from congenic C57BL/6 (H-2b, Thy1.1). Expression of chemokine receptors, homing molecules, and IFN-γ expressed on donor-derived cells were analyzed at indicated days and tissues after BMT by FACS. (A) α4β7 and CCR9. (B) E-selectin ligand and P-selectin ligand. (C) CCR5 and CXCR3. (D) IFN-γ. ND indicates not done. Samples were not obtained because all GVHD control mice died by day 9. LN indicates lymph node. Error bars represent SD. *P < .05; **P < .01.

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