Figure 1
Figure 1. Correlation of XCI patterns obtained with the use of 3 different methods. (A) HUMARA assay versus TaqMan SNP assay at the IDS locus. For each individual, the %Sup measured by HUMARA was compared with the percentage of IDS allele obtained with the TaqMan SNP assay, which was quantitatively closer to the HUMARA value. Data from both assays were available for 90 women. (B) HUMARA assay versus suppressive PCR assay at the IDS locus. The %Sup obtained by HUMARA was compared with the percentage of IDS allele obtained with the suppressive PCR assay, which was quantitatively closer to the HUMARA value. Data from both assays were available for 67 women. (C) TaqMan SNP assay versus suppressive PCR assay. The percentage of IDS allele obtained with the TaqMan SNP assay was compared with that obtained with the suppressive PCR assay. Data from both assays were available for 60 women. Those aged 44 to 65 years are represented by ▵, whereas those older than 65 years are represented by ●.

Correlation of XCI patterns obtained with the use of 3 different methods. (A) HUMARA assay versus TaqMan SNP assay at the IDS locus. For each individual, the %Sup measured by HUMARA was compared with the percentage of IDS allele obtained with the TaqMan SNP assay, which was quantitatively closer to the HUMARA value. Data from both assays were available for 90 women. (B) HUMARA assay versus suppressive PCR assay at the IDS locus. The %Sup obtained by HUMARA was compared with the percentage of IDS allele obtained with the suppressive PCR assay, which was quantitatively closer to the HUMARA value. Data from both assays were available for 67 women. (C) TaqMan SNP assay versus suppressive PCR assay. The percentage of IDS allele obtained with the TaqMan SNP assay was compared with that obtained with the suppressive PCR assay. Data from both assays were available for 60 women. Those aged 44 to 65 years are represented by ▵, whereas those older than 65 years are represented by ●.

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