Figure 5
Figure 5. Survival of TC- and HSC/HPC-transplanted animals. Animals that received transplants of HSCs/HPCs transduced with the oncogenes LMO2 (A), TCL1 (B), ΔTrkAhigh (C), or ΔTrkAlow (D) developed hematologic malignancies after characteristic latency periods (A-D, ). Control animals that received transplants of MP91-eGFP (E) and recipients of TC transplants survived throughout the observation time (A-E, —) with no indication of leukemia/lymphoma.

Survival of TC- and HSC/HPC-transplanted animals. Animals that received transplants of HSCs/HPCs transduced with the oncogenes LMO2 (A), TCL1 (B), ΔTrkAhigh (C), or ΔTrkAlow (D) developed hematologic malignancies after characteristic latency periods (A-D, ). Control animals that received transplants of MP91-eGFP (E) and recipients of TC transplants survived throughout the observation time (A-E, —) with no indication of leukemia/lymphoma.

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