Wt→β2M^−/− chimeric recipients are resistant to CD8-mediated GVHD. Shown is percentage weight change versus day after alloBMT from 2 independent experiments. Numbers of mice per group in each repetition are listed (separated by commas; *P < .05, CD8 recipients vs recipients of only TCD C3H.SW BM). Weight change was not significantly different at any time point comparing wt→β2M^−/− recipients of only C3H.SW TCD BM and TCD BM plus CD8 cells.