Alignment of the human, dog, mouse, rat, and cow NH₂-terminus of band 3. Alignment of the first 65 amino acids of human, dog, mouse, rat, and cow AE1 using the CLUSTALW program (http://align.genome.jp//). Asterisks (*) indicate complete sequence conservation; double and single dots, less conservation; (^) symbols, the 2 tyrosine phosphorylation sites at the NH₂-terminus of human band 3.