Schematic of platelet model compartmentalization and reactions. The full model comprises 5 compartments, 70 species, 77 reactions, and 132 kinetic parameters (Table 1). Three-dimensional compartments: extracellular (EX), cytosolic, and DTS. Two-dimensional compartments: PM and DTS inner membrane (IM). IPP indicates inositol phosphate phosphatase; IP₂P, inositol bisphosphate phosphatase; IP₃P, inositol trisphosphate phosphatase; DAG, diacylglycerol; PA, phosphatidic acid; CDP, CDP-DAG.