Observed and simulated gene-marking data. Shown is the percentage of marked granulocytes as a function of time (from 0 to 500 days) in 11 baboons, in 12 virtual baboons simulated by using mouse parameters (λ = 1 replication per 2.5 weeks; ν = 1 differentiation per 3.4 weeks; α = 1 apoptosis per 20 weeks; μ = 6.9 weeks⁵ ; R₀ = 300), in 12 virtual baboons simulated by using cat parameters (λ = 1 replication per 8.3 weeks; ν = 1 differentiation per 12.5 weeks; α = 1 apoptosis per 50 weeks; μ = 6.7 weeks⁴ ; R₀ = 300), and in 12 virtual baboons simulated by using the best estimates of baboon parameter values (λ = 1 replication per 36 weeks; ν = 1 differentiation per 51 weeks; α = 1 apoptosis per 257 weeks; μ = 6.7 weeks; R₀ = 300). For simulated data, the trajectories shown are the first 12 of 1000 virtual baboons.