Figure 4
Figure 4. Prednisolone increases CD20 expression in vitro. CD20 expression levels (MFI values) of viable leukemic cells of 10 ALL samples after incubation for 3 days with various concentrations of prednisolone (none; 0.05-5 μg/mL) are shown (individual patients are characterized by specific symbols). In vivo expression changes in samples taken at diagnosis and day 8 (after the prednisolone prephase) among the same patients are shown for comparison. Note patient-specific modulation patterns.

Prednisolone increases CD20 expression in vitro. CD20 expression levels (MFI values) of viable leukemic cells of 10 ALL samples after incubation for 3 days with various concentrations of prednisolone (none; 0.05-5 μg/mL) are shown (individual patients are characterized by specific symbols). In vivo expression changes in samples taken at diagnosis and day 8 (after the prednisolone prephase) among the same patients are shown for comparison. Note patient-specific modulation patterns.

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