Disseminated thrombosis in WT versus GSK3β^+/− mice. A combination of collagen (170 μg/kg) and epinephrine (350 μM/kg) was injected into the tail vein of sedated mice (7 WT, 6 GSK3β^+/−), and the time until breathing stasis was recorded for 10 minutes. The number of surviving mice is graphed as a function time in minutes (WT, ○, GSK3β^+/−, ●).