Cytokine profiles in follicular lymphoma and follicular hyperplasia. Scatterplots of designated cytokine protein concentrations in FL (N = 50) and FH (N = 23). Cytokine protein concentrations (picogram/mg of total protein for each tissue lysate) were determined by multiplex sandwich immunoassay system (“Methods”) and are depicted on a log10 scale. Median cytokine concentrations for FL and FH are designated with horizontal bars on the scatterplots and are listed beneath the plot for each group, with the P value for comparison of the 2 groups. FL samples representing grade 3B are indicated by ○. (A-D) Monocyte/macrophage-associated cytokine profiles in follicular lymphoma and follicular hyperplasia. (A) IL-1β. (B) IL-8. (C) IL-10. (D) IL-12 p70. (E-G) Th1-associated cytokine profiles in FL and FH. (E) TNF-α. (F) Interferon-γ. (G) IL-2. (H-J) Th2-associated cytokine profiles in FL and FH. (H) IL-4. (I) IL-5. (J) IL-13.
