Figure 5
Figure 5. Contribution of CD11c− hematopoietic cells in memory CD8 T-cell homeostasis. BM cells were isolated from IL-15Rα−/−, CD11c-IL-15RαTg-1, and Wt mice (all CD45.2+) and transferred into lethally irradiated Wt hosts (CD45.1+). CD8 T cells were isolated from VSV-infected Thy1.1+ cells, labeled with CFSE, and transferred into the various BM chimeras after lymphocyte reconstitution (between 8 and 12 weeks after BM transfer). Six weeks after transfer, CFSE dilution of donor cells was measured.

Contribution of CD11c hematopoietic cells in memory CD8 T-cell homeostasis. BM cells were isolated from IL-15Rα−/−, CD11c-IL-15RαTg-1, and Wt mice (all CD45.2+) and transferred into lethally irradiated Wt hosts (CD45.1+). CD8 T cells were isolated from VSV-infected Thy1.1+ cells, labeled with CFSE, and transferred into the various BM chimeras after lymphocyte reconstitution (between 8 and 12 weeks after BM transfer). Six weeks after transfer, CFSE dilution of donor cells was measured.

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