Figure 2
Figure 2. MTA3 and BCL6 expression are highly correlated in primary DLBCLs. (A) BCL6 and MTA3 expression was examined in a panel of 176 patients with DLBCL by expression microarray analysis. A heat map graphically representing BCL6 and MTA3 mRNA abundance is shown. (B) Scatterplot representation of correlation between BCL6 and MTA3 mRNA levels in all patients with DLBCL. The y- and x-axes correspond to mRNA levels in arbitrary units. The lines are regression line with confidence intervals (“Microarray expression analysis in human DLBCLs”). (C) Immunohistochemistry was performed in tissue microarrays (TMAs) containing 74 patients with DLBCL with BCL6, MTA3, and CD20 antibodies. Representative micrographs are shown of a DLBCL sample stained for BCL6 + CD20 or MTA3 + CD20 as labeled. (D) Scatterplot representation of correlation between BCL6 and MTA3 protein levels in all 127 patients with DLBCL. The y- and x-axes represent protein expression levels.

MTA3 and BCL6 expression are highly correlated in primary DLBCLs. (A) BCL6 and MTA3 expression was examined in a panel of 176 patients with DLBCL by expression microarray analysis. A heat map graphically representing BCL6 and MTA3 mRNA abundance is shown. (B) Scatterplot representation of correlation between BCL6 and MTA3 mRNA levels in all patients with DLBCL. The y- and x-axes correspond to mRNA levels in arbitrary units. The lines are regression line with confidence intervals (“Microarray expression analysis in human DLBCLs”). (C) Immunohistochemistry was performed in tissue microarrays (TMAs) containing 74 patients with DLBCL with BCL6, MTA3, and CD20 antibodies. Representative micrographs are shown of a DLBCL sample stained for BCL6 + CD20 or MTA3 + CD20 as labeled. (D) Scatterplot representation of correlation between BCL6 and MTA3 protein levels in all 127 patients with DLBCL. The y- and x-axes represent protein expression levels.

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