Figure 1
![Figure 1. Modulation of platelet aggregation and protein release by aspirin. Equal volumes of platelets (2.5 × 108) were stimulated with ADP, TRAP, and collagen in the presence or absence of low-dose aspirin (20 μM). The aggregation response was plotted (mean ± standard deviation [SD] of 3 independent experiments using different donors) (A). Platelet releasate from a single representative donor was visualized using coomassie-stained (4%-20% acrylamide) and silver-stained (16% acrylamide) gels (B). Thromboxane levels in the platelet releasate (mean ± SD of 3 experiments) were plotted for each fraction (C).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/109/11/10.1182_blood-2006-07-038539/4/zh80110704300001.jpeg?Expires=1738203810&Signature=VZDSnYFXLt9AsOBcimGyGpY-~GlM2q3gw~8QEbfXlMvT0O9SDGABSO-MiMBDgNziRNFiarjz~2weoyMwBX4t6zwd0bTj~pp6bYY7-SUOC2GnCZc57YSCs0n5NEJa8De6d3vSqYOheNyc52xuUUaI3mvohxKunVmaM1XNHI7ddkof0Nk4tZEJ3v5-KjJi0lPIhULYL53ODubzVlgpvzs3K5l38fDBbp00o0p9Apd7JZIfI243efApTor4yzO1YdOVv6-hUICS6-jIL0y9Mrd7psQ3cDPS2fQTL6PPpKFxi8fZzQ2uRlElHnQh9ty1AYjVMrFiRMTh7AxZIPW7Fb6csg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Modulation of platelet aggregation and protein release by aspirin. Equal volumes of platelets (2.5 × 108) were stimulated with ADP, TRAP, and collagen in the presence or absence of low-dose aspirin (20 μM). The aggregation response was plotted (mean ± standard deviation [SD] of 3 independent experiments using different donors) (A). Platelet releasate from a single representative donor was visualized using coomassie-stained (4%-20% acrylamide) and silver-stained (16% acrylamide) gels (B). Thromboxane levels in the platelet releasate (mean ± SD of 3 experiments) were plotted for each fraction (C).
