Progression-free, event-free, and overall survival. (A) Progression-free survival (PFS) from second transplantation (median: 31 months for second ASCT and not reached for allo-RIC, P = .08; PFS at 5 years with second ASCT and allo-RIC 34.9% [95% CI 22.6%-47.2%] vs 61% [95% CI (confidence interval) 39.8%-82.2%]). (B) Event-free survival (EFS) from second transplantation (median: 26 months for second ASCT and 19.6 months for allo-RIC, P = .4; EFS at 5 years with second ASCT and allo-RIC 31% [95% CI 19.4%-42.3%] vs 41% [95% CI 20.2%-62%]). (C) Overall survival (OS) from second transplantation (median: 58 months for second ASCT and not reached for allo-RIC, P = .9; OS at 5 years with second ASCT and allo-RIC 60% [95% CI 48.3%-73%] vs 61.8% [95% CI 40.6%-82%]).