Illustrative representation of the size of the actual identifiable TCR-Vβ expansion present in each patient (as percentage of total PB CD4⁺ T cells) in comparison with the size of the corresponding TCR-Vβ family observed in a cohort of age-matched healthy subjects (n = 15). Gray bars correspond to patients, each one identified by the corresponding case number, while white bars and horizontal lines correspond to the mean value and 1 SD found in healthy controls, respectively.