Thrombin generation in FV-deficient plasma reconstituted with 100% FV and in normal plasma. Thrombin generation was measured in FV-deficient plasma (pooled plasma from patients GK 502, GK 505, and GK 506) reconstituted with 100% FV (●) and in normal plasma (○) after triggering coagulation with (A) 1.36 pM TF, (B) 13.6 pM TF, and (C) 13.6 pM TF in the presence of 12 nM APC.