Figure 3
Figure 3. Effect of antirat TNFα and antirat IL-4 antisera on subacute (4-hour) Ang-II-induced leukocyte adhesion to rat mesenteric arterioles. Rats were treated intraperitoneally with PBS (buffer; n = 5) or 1 nM Ang-II (n = 5). Some animals were pretreated with the antirat TNFα antiserum (1 mL per rat intravenously; n = 6), or the antirat IL-4 antiserum (1 mL per rat intravenously; n = 6), or a combination of both antisera (n = 4) 15 minutes before the administration of Ang-II. Results are mean (± SEM). *P < .05 or **P < .01 relative to the PBS group; + P < .05 or ++ P < .01 relative to the Ang-II group.

Effect of antirat TNFα and antirat IL-4 antisera on subacute (4-hour) Ang-II-induced leukocyte adhesion to rat mesenteric arterioles. Rats were treated intraperitoneally with PBS (buffer; n = 5) or 1 nM Ang-II (n = 5). Some animals were pretreated with the antirat TNFα antiserum (1 mL per rat intravenously; n = 6), or the antirat IL-4 antiserum (1 mL per rat intravenously; n = 6), or a combination of both antisera (n = 4) 15 minutes before the administration of Ang-II. Results are mean (± SEM). *P < .05 or **P < .01 relative to the PBS group; + P < .05 or ++ P < .01 relative to the Ang-II group.

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