Figure 1
Experimental design. Murine bone marrow cells were transduced with retroviral vector coexpressing MGMT P140K and eGFP and transplanted into syngeneic lethally irradiated primary recipient mice. Primary recipients received either 105 or 4 × 105 transduced BM cells. Cohorts of both groups were treated monthly with different dosages of BCNU and O6BG as indicated.
