CD163 functions as an adhesion receptor for erythroblasts. (A) Surface expression of CD163, as identified by fluorescence-activated cell sorter (FACS) staining using mAb EDhu1, on CHO cells stably expressing human CD163 (CHO-CD163) or empty vector (CHO). (B) K562 erythroblastic leukemic cell binding to CHO cells expressing CD163. Data shown are the means ± standard deviation (SD) from 4 independent experiments. (C) Binding of K562 cells or freshly isolated rat erythroblasts to fluorescent beads coated with either CD163-Fc or ICAM3-Fc protein. Data shown are the means ± SD from 3 independent experiments.