Figure 5
Effect of α-based radioimmunotherapy on growth of individual Raji xenografts. Individual tumor sizes versus time after intravenous injection of NaCl (A); 20, 100, and 250 μg cold rituximab (B-D); 50, 200, 400, and 1000 kBq/mL 227Th-p-benzyl-DOTA-rituximab (E-H); intravenous injection of 200 and 400 kBq/mL 227Th-p-benzyl-DOTA-trastuzumab (I); or intravenous injection of 7.5, 15, and 30 MBq/kg 90Y-ibritumomab-tiuexetan (J-L).
