Effect of α-based radioimmunotherapy on growth of Raji xenografts. Mean tumor size versus time after intravenous injection of cold rituximab, 50, 200, and 400 kBq/mL ²²⁷Th-p-benzyl-DOTA-rituximab (A); intravenous injection of 200 and 400 kBq/mL ²²⁷Th-p-benzyl-DOTA-trastuzumab (B); or intravenous injection of 7.5, 15, and 30 MBq/kg ⁹⁰Y-ibritumomab-tiuexetan (C). The data for cold rituximab were pooled from groups of mice injected with 20, 100, and 250 μg rituximab. Error bars represent SE. The tumors were not removed from the calculation of mean tumor size when the mice were censored.