Figure 2
Figure 2. Summary of Phase 3 results. Panel A shows the reduction in the -2 log likelihood when comparing the best 1 SNP, 2 SNP,…9 SNP model from the study data (solid line) as well as expected reduction due to chance (dashed line). Panel B ranks the percentage of 1000 stepwise bootstrap Cox models in which a SNP was included. The top 4 SNPs in the bootstrap model are the same 4 SNPs in the best 4-SNP risk model.

Summary of Phase 3 results. Panel A shows the reduction in the -2 log likelihood when comparing the best 1 SNP, 2 SNP,…9 SNP model from the study data (solid line) as well as expected reduction due to chance (dashed line). Panel B ranks the percentage of 1000 stepwise bootstrap Cox models in which a SNP was included. The top 4 SNPs in the bootstrap model are the same 4 SNPs in the best 4-SNP risk model.

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