Figure 3
Figure 3. Bar plot showing the percentage of absent gene expression cells derived from Affymetrix microarray data in the 4 main gene subsets. Different series of cases are shown: mBL and non-mBL in which DNA methylation profiling was performed, an independent series of maB-NHLs, 2 different series of healthy hematopoietic controls, normal brain tissues, and a mixture of other normal tissues. P values comparing the percentage of absent detection calls in the meL/umC and dmeL/umC groups versus the umL/umC group are also shown. These analyses indicate that genes of the meL/umC and dmeL/umC groups globally show a higher proportion of absent detection calls than genes of the umL/umC group, both in lymphomas and normal hematopoietic tissues but not in normal nonhematopoietic tissues. dmeL/umC indicates differentially methylated in lymphoma subtypes and unmethylated in controls; mBL, molecular Burkitt lymphoma; meL/meC, methylated in lymphomas and controls; meL/umC, methylated in all lymphomas but not in controls; and umL/umC, unmethylated in lymphomas and controls.

Bar plot showing the percentage of absent gene expression cells derived from Affymetrix microarray data in the 4 main gene subsets. Different series of cases are shown: mBL and non-mBL in which DNA methylation profiling was performed, an independent series of maB-NHLs, 2 different series of healthy hematopoietic controls, normal brain tissues, and a mixture of other normal tissues. P values comparing the percentage of absent detection calls in the meL/umC and dmeL/umC groups versus the umL/umC group are also shown. These analyses indicate that genes of the meL/umC and dmeL/umC groups globally show a higher proportion of absent detection calls than genes of the umL/umC group, both in lymphomas and normal hematopoietic tissues but not in normal nonhematopoietic tissues. dmeL/umC indicates differentially methylated in lymphoma subtypes and unmethylated in controls; mBL, molecular Burkitt lymphoma; meL/meC, methylated in lymphomas and controls; meL/umC, methylated in all lymphomas but not in controls; and umL/umC, unmethylated in lymphomas and controls.

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