Overall survival according to CLLU1 expression levels in different age groups. (A) In patients with CLL younger than 70 years at diagnosis (n = 92) the median overall survival was 6.5 years for patients with high CLLU1 expression levels (n = 41; 45%) but not reached after 14.9 years in patients with low CLLU1 expression levels (n = 51; 55%). (B) In patients 70 years of age or older at diagnosis (n = 83) there was no significant difference in overall survival between groups with high (n = 33; 40%) and low (n = 50; 60%) CLLU1 expression levels.