p53 pathway activation. (A) Hierarchic clustering of the samples taken before (blue) and after (red) radiation based on the 25 known p53 transcripts regulated by low-dose radiation. (B) p53 and MKI67 immunostaining was performed on paraffin sections of FL biopsies take before and after low-dose radiation. Images were acquired with a ColorView (Mitsubishi, Tokyo, Japan) SIS CCD camera (20×, PlanApo, 20×/0.09) and DP-Soft (Muenster, Germany) CVI 3.2 software. One representative field is shown.