Age- and sex-adjusted significant associations of various IgG aPL antibodies in the upper tertile with anamnestic clinical end points. No significant association was found between IgM antibodies in the upper tertile and anamnestic clinical end points. IgG and IgM antibodies were measured at enrollment of 112 patients in the WAPS study. The numbers of patients with events on the number of patients with antibodies in the highest tertile are reported in brackets. APS indicates that arterial thrombosis, venous thrombosis, and obstetric events were combined; total thrombosis indicates that anamnestic arterial and venous thrombosis were combined.