Figure 8
Figure 8. Effects of mast cells, IL-12, and IL-23 on survival after CLP. (A) Effect of transplantation of WT-BMMCs on survival of p40−/− mice exposed to CLP. Survival rates of p40−/− mice (5 mice/group; ■), and p40−/− mice that received a transplant of WT-BMMCs (4 mice/group; ●) after CLP induction are shown. (B) Effect of IL-12 and IL-23 on survival of W/Wv mice exposed to CLP. Survival rates of W/Wv mice with intraperitoneal saline injection (5 mice/group; ■), W/Wv mice with intraperitoneal murine IL-12 injection (8 mice/group; ▴), and W/Wv mice with intraperitoneal murine IL-23 injection (10 mice/group; ●) following CLP induction are shown.

Effects of mast cells, IL-12, and IL-23 on survival after CLP. (A) Effect of transplantation of WT-BMMCs on survival of p40−/− mice exposed to CLP. Survival rates of p40−/− mice (5 mice/group; ■), and p40−/− mice that received a transplant of WT-BMMCs (4 mice/group; ●) after CLP induction are shown. (B) Effect of IL-12 and IL-23 on survival of W/Wv mice exposed to CLP. Survival rates of W/Wv mice with intraperitoneal saline injection (5 mice/group; ■), W/Wv mice with intraperitoneal murine IL-12 injection (8 mice/group; ▴), and W/Wv mice with intraperitoneal murine IL-23 injection (10 mice/group; ●) following CLP induction are shown.

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