Figure 7
Figure 7. Bacterial counts, neutrophil migration, and IFN-γ concentration in the peritoneal cavity. (A) Bacterial counts in the peritoneal fluids collected from CLP-treated mice at 6 hours after CLP surgery. WBB6 F1+/+ (wild type; ●), WBB6 F1-W/Wv (mast-cell deficient; ○), wild-type BMMC–reconstituted WBB6 F1-W/Wv (▴), and p40−/− BMMC–reconstituted WBB6 F1-W/Wv mice (▵). Results are expressed as log10 of CFU per cavity (n = 4 mice). Horizontal bar represents the mean. (B) Neutrophil migration into the peritoneal cavity of CLP-treated mice at 0 or 6 hours after CLP surgery. WBB6 F1+/+ (■), WBB6 F1-W/Wv (□), wild-type BMMC–reconstituted WBB6 F1-W/Wv (hatched bar), and p40−/− BMMC–reconstituted WBB6 F1-W/Wv mice (dotted bar) in panels B-C. Data represent mean ± SD of 5 mice and *P < .05; significantly different from the mean value of the corresponding control in panels B-C. (C) Concentration of IFN-γ in the peritoneal cavity of CLP-treated mice at 0 or 6 hours after CLP surgery.

Bacterial counts, neutrophil migration, and IFN-γ concentration in the peritoneal cavity. (A) Bacterial counts in the peritoneal fluids collected from CLP-treated mice at 6 hours after CLP surgery. WBB6 F1+/+ (wild type; ●), WBB6 F1-W/Wv (mast-cell deficient; ○), wild-type BMMC–reconstituted WBB6 F1-W/Wv (▴), and p40−/− BMMC–reconstituted WBB6 F1-W/Wv mice (▵). Results are expressed as log10 of CFU per cavity (n = 4 mice). Horizontal bar represents the mean. (B) Neutrophil migration into the peritoneal cavity of CLP-treated mice at 0 or 6 hours after CLP surgery. WBB6 F1+/+ (■), WBB6 F1-W/Wv (□), wild-type BMMC–reconstituted WBB6 F1-W/Wv (hatched bar), and p40−/− BMMC–reconstituted WBB6 F1-W/Wv mice (dotted bar) in panels B-C. Data represent mean ± SD of 5 mice and *P < .05; significantly different from the mean value of the corresponding control in panels B-C. (C) Concentration of IFN-γ in the peritoneal cavity of CLP-treated mice at 0 or 6 hours after CLP surgery.

Close Modal

or Create an Account

Close Modal
Close Modal