Drm/gremlin immunohistochemistry in human lung cancers. Endothelial cells of tumor vessels (arrows) show a strong Drm/gremlin immunoreactivity in human lung squamous-cell carcinoma (A) and adenocarcinoma (B-C). Squamous tumor cells are weakly immunoreactive (A). No or very weak immunoreactivity is detected in nonneoplastic lung tissue adjacent to the tumor (D). Original magnification, × 200 (A,D); × 400 (B,C).