Drm/gremlin expression in tumor xenografts. (A) Drm/gremlin immunostaining of tumor xenografts originated in nude mice by subcutaneous injection of human endometrial adenocarcinoma HEC-1-B–derived cells. Note the Drm/gremlin immunoreactivity in tumor stroma, absent in tumor parenchyma. (B) Negative control in which the primary antibody was omitted. Original magnification, × 200. (C) RT-PCR analysis of 4 tumor xenografts (T) using murine and human specific Drm/gremlin primers.