Transplantation of DTG lymphoma cells into immune-deficient SCID mice. (A) Necropsy of a SCID mouse that received a transplant of cells from a cell line derived from a DTG mouse lymphoma (arrows). (B) H&E paraffin sections of the SCID peritoneal tumor bearing the DTG tumor cells from low (top panel; original magnification, ×100) to high magnification (bottom panel, original magnification, ×400). (C) Immunohistochemical analysis of the transplanted lymphoma from a SCID mouse showing the expression of cyclin D1, CD5, and B220 (original magnification, ×400).