AMN107 treatment of BCR-ABL point mutant and wild-type BCR-ABL–expressing Ba/F3 cell lines. This figure shows the results of AMN107 treatment of different BCR-ABL point mutants and wild-type Bcr-Abl–expressing Ba/F3 cell lines using a wide range of concentrations for 72 hours. The dose response curves obtained from the MTS assay are presented in a semilog plot. Error bars indicate the standard deviation of the mean for each dose.