Representative recordings of whole-cell current measurements in HbA cells. (A-B) Oxygenated HbA cells. (C-D) Deoxygenated HbA cells. Measurements were made using Na⁺-containing bath and pipette solutions. Current measurements were only included for analysis in this study after they remained stable for 3 successive recordings over a 6 minute period. Averaged results for panels A and C are presented in panels B and D as means ± SEM, n = 13 (oxygenated cells) and n = 34 (deoxygenated cells).