Figure 5
Figure 5. Eosinophil resolution after OVA challenge is delayed in Siglec-F−/− mice and peribronchial-cell apoptosis is decreased. (A) Mice were killed 7 days after the last OVA challenge. Eosinophils/bronchus were enumerated, as in Figure 4. (B) Eosinophils in the BAL were counted, as described in “Materials and methods.” (C) Lung sections were stained for apoptotic cells by TUNEL assay (n = 4, data representative of 2 experiments). (A,C) *P < .05; ***P < .001.

Eosinophil resolution after OVA challenge is delayed in Siglec-F−/− mice and peribronchial-cell apoptosis is decreased. (A) Mice were killed 7 days after the last OVA challenge. Eosinophils/bronchus were enumerated, as in Figure 4. (B) Eosinophils in the BAL were counted, as described in “Materials and methods.” (C) Lung sections were stained for apoptotic cells by TUNEL assay (n = 4, data representative of 2 experiments). (A,C) *P < .05; ***P < .001.

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