Kaplan-Meier plots demonstrating the effect of LOH on patient survival. (A,B) The effect of UPD and copy number change on overall survival is shown. UPD present (n = 53), UPD absent (n = 64), CN present (n = 20), CN absent (n = 97). (C,D) The overall survival of MDS patients according to the presence of deletions or amplifications, respectively, is shown. Deletion present (n = 13), deletion absent (n = 104), amplification present (n = 8), amplification absent (n = 109). Two patients did not have any follow-up data.