Platelet-adherent leukocytes correlate with systemic cysLT production. (A) Baseline urinary LTE₄ (top) and TXB₂ (bottom) levels analyzed by gas chromatography-mass spectrometry from nonasthmatic controls (n = 8), ATA controls (n = 9) and subjects with AERD (n = 10). Data are expressed as mean + SD (★★★P < .001). (B) Baseline urinary LTE₄ levels plotted against the corresponding percentages of platelet-adherent eosinophils (top), neutrophils (middle), and monocytes (bottom) in the peripheral blood of each subject. Effect size, determined with Pearson correlation coefficient, is denoted as an r value displayed for each cell type. White circles, nonasthmatic controls; gray squares, ATA controls; black triangles, AERD subjects.