Transport properties of the transition zone. (A) A representative image of a thrombus at 3 minutes and 20 minutes postinjury showing platelet deposition (blue) and P-selectin exposure (red) at 3 minutes and 20 minutes. Also shown are the stable core (cyan outline) 20 minutes postinjury, and the transition zone (green outline) at 3 minutes postinjury. (B) Eight of the injuries had transition zones (green) large enough (>10 μm²) to be analyzed in addition to the core (red) and shell (blue) regions for their average cAlb decay curves (±SD). (C) For those same images in panel A, the resulting cAlb t_1/2 time heat maps are shown with the LTR highlighted (cyan). The LTR is defined as the P-selectin(+) region plus the transition zone (ie, the P-selectin(+) region at 20 minutes postinjury). (D) Analysis of the LTR (cyan) transport compared with the shell (blue) transport properties using cAlb.