Polygenic risk score distribution by InterLymph CLL and controls and GEC CLL, MBL, controls, and Mayo Clinic controls. Histograms of polygenic risk scores (x-axis) and density (y-axis). (A) InterLymph CLL (dashed red line) and controls (solid purple line). (B) Mayo controls (purple), GEC controls (green), GEC MBL (blue), and GEC CLL (red). Vertical lines indicate the median for the corresponding polygenic risk score distribution.