Platelet GPVI is involved in platelet influx and activation and platelet–leukocyte complex formation in the lung. Mice were injected with JAQ1 or IgG control antibody, infected with K pneumoniae via the airway, and sacrificed 12, 36, or 42 hours after infection. (A) Platelet counts. (B) Platelet P-selectin expression. (C-D) Platelet–neutrophil complex formation. (E-F) Platelet–macrophage complex formation. (C,E) Representative histogram of CD61 expression on neutrophils (C) of macrophages (E) in the BALF. Data are presented as box and whisker plots of 8 mice per group. *P < .05, **P < .005 vs IgG control.