OS and TNT. (A) OS on an ITT basis (n = 27) and TNT on an evaluable basis (n = 17). Median OS and median TNT were not reached. OS at 1 and 3 years was 65% and 56%, respectively. At 1 and 3 years, 88% and 79% of evaluable patients (n = 17) had not progressed to further treatment. (B) Median OS was not reached in those patients who achieved a VGPR or better, with 92% alive at 2 years; median OS was 9 months in patients who did not achieve a VGPR. Cum survival, cumulative survival.