Figure 4.
Figure 4. Intersecting sets of transcripts across EVs and whole cell content. Depiction of all possible transcript overlap sets among the DLBCL cell lines, primary samples, normal B cells, and their corresponding EVs. Samples are listed on the left with the blue bar indicating the number of expressed RNA transcripts. On the right panel, the average of TPM values was plotted in this graph for each transcript isoform from each sample type (EV-normal B, EV-primary DLBCL, etc). Then, to restrict the analysis to the most abundant transcripts, the top 5% expressed transcripts from each sample type were selected and analyzed for overlapping transcripts. The intersections of sets are a matrix in which the rows represent the sets and the columns represent their intersections. The number of shared transcripts is indicated in the y-axis. Overlaps are sorted in decreasing size, and the shaded circles connected by solid lines in the lower panel indicate the intersecting samples.

Intersecting sets of transcripts across EVs and whole cell content. Depiction of all possible transcript overlap sets among the DLBCL cell lines, primary samples, normal B cells, and their corresponding EVs. Samples are listed on the left with the blue bar indicating the number of expressed RNA transcripts. On the right panel, the average of TPM values was plotted in this graph for each transcript isoform from each sample type (EV-normal B, EV-primary DLBCL, etc). Then, to restrict the analysis to the most abundant transcripts, the top 5% expressed transcripts from each sample type were selected and analyzed for overlapping transcripts. The intersections of sets are a matrix in which the rows represent the sets and the columns represent their intersections. The number of shared transcripts is indicated in the y-axis. Overlaps are sorted in decreasing size, and the shaded circles connected by solid lines in the lower panel indicate the intersecting samples.

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