RNA species found in EVs and cells. (A) DLBCL cell lines OCI-Ly3, HBL1, TMD8, OCI-Ly1, and OCI-Ly7, (B) EVs from DLBCL cell lines OCI-Ly3, HBL1, TMD8, OCI-Ly1, and OCI-Ly7, (C) whole cell DLBCL primary samples DLBCL1, DLBCL2, DLBCL3, DLBCL4, DLBCL5, (D) EVs from DLBCL primary sample DLBCL6, (E) whole cell normal B cells NB1, NB2, and NB3, and (F) EVs from normal B cells B2. EVs contain a variety of RNA species with enrichment for noncoding RNAs, long intergenic noncoding RNAs (lincRNAs), snoRNAs, and snRNAs. Quantities are displayed as the sum of average transcripts per million (TPM) per RNA class. rRNA, ribosomal RNA.