The POD24 Prognostic Index (POD24-PI). (A) The POD24-PI is calculated as the sum of individual clinical and gene mutation predictor values weighted by their individual coefficients. (B) Kaplan-Meier curves for failure-free survival (FFS), and (C) overall survival (OS) for patients from the GLSG and BCCA cohorts according to POD24-PI status. Numbers in parentheses indicate patients with event/number of patients per subgroup.