Weight status and EFS. Cox regression analysis was used to evaluate the effect of weight category at diagnosis and MRD on postinduction EFS. At early ∼2-year median follow-up, NCI/Rome risk category–adjusted survival curves revealed poorer survival for (A) children overweight or obese at time of diagnosis and (B) an additional contribution of BMI category (lean or not lean) to EFS even within MRD groups (end-induction MRD positive or negative). Survival curves plotted from time of diagnosis for clarity.