The radiological and genetic diagnosis of Xq28 linked moyamoya in hemophilia A patient. (A) MRI angiography, the arrows show truncation of the internal carotid arteries. (B) Long-range PCR products in 4 members of the family. (C) NGS trace (the location shown on chromosome ideogram) below genes located within the region, which corresponds to the long-range PCR-confirmed Xq28 deletion in a SHAM patient (indicated with red box).