Figure 2
Examples of 3 typical clonal structures of ATL cases. Each sector in the pie charts depicts the relative abundance of the respective integration site. (A) Typical “monoclonal” ATL tumor sample; PVL = 63% (relative abundance of dominant clone = 97% of PVL). (B) Two equally abundant integration sites (relative abundance respectively 44% and 39% of PVL); PVL = 9%. (C) ATL with dominant clone and additional intermediate-abundance clone (relative abundance respectively 67% and 23% of PVL); PVL = 241%.

Examples of 3 typical clonal structures of ATL cases. Each sector in the pie charts depicts the relative abundance of the respective integration site. (A) Typical “monoclonal” ATL tumor sample; PVL = 63% (relative abundance of dominant clone = 97% of PVL). (B) Two equally abundant integration sites (relative abundance respectively 44% and 39% of PVL); PVL = 9%. (C) ATL with dominant clone and additional intermediate-abundance clone (relative abundance respectively 67% and 23% of PVL); PVL = 241%.

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